Letrozol AbZ 2,5 mg

5,00 15,00 

SKU: N/A Category:


Contraindications to the use of letrozole

  • Endocrine conditions specific to the reproductive period;
  • pregnancy;
  • lactation (breastfeeding);
  • Infancy (efficacy and safety in children has not been established);
  • hypersensitivity to the components of the drug.

Caution: the drug should be used in cases of lactase deficiency, lactase intolerance, glucose-galactose malabsorption syndrome. There are no data on the use of letrozole in patients with a CK < 30 ml/min (the ratio of potential risk to expected treatment effect should be carefully considered before prescribing the drug to such patients).

Method of administration

  • The drug is taken orally, irrespective of meals.
  • The recommended dose of letrozole is 2.5 mg once/day, daily, long-term (for 5 years or until relapse).
  • As extended adjuvant therapy, treatment should be continued for 4 years (not more than 5 years).
  • Letrozole should be discontinued if there are signs of disease progression.
  • In patients with end-stage or metastatic cancer, treatment with letrozole should be continued as long as there is tumour progression.
  • No dose adjustment of letrozole is required in elderly patients.
  • No dose adjustment is required for hepatic or renal impairment (CK >10 ml/min). However, in cases of severe hepatic impairment (Child-Pugh class C), patients require continuous medical supervision.
  • Use of letrozole during pregnancy and lactation
    Contraindicated use during pregnancy and lactation (breastfeeding).

Additional information

substance active


Amount of substance, mg


formulaire de discharge


1 compressed, mg


Plaquettes thermoformed by package, pieces



AbZ Pharma GmbH

volume de commande

1 blister of 10 compresses, 1 pack (3 blisters)


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